Application I
Time-resolved monitoring of the transepithelial electrical resistance
(TER) of primary cultured endothelial cells derived from porcine brain
microvessels, incubated in serum-free medium supplemented with
hydrocortisone (orange curve) and without hydrocortisone (blue curve):
the experimental data reveal that the TER of the confluent cell layer
increases with time in the presence of hydrocortisone. This effect is
attributed to a pronounced barrier strengthening of the cerebral
endothelial cells.
Graph adapted from Wegener et al., BioTechniques 37, 590 (2004).